HGVbaseG2P - Phenotype Method Report

Phenotype Method Report - Parkinson's disease status (HGVPM3)

Phenotype summary

HGVbaseG2P identifier	HGVPM3
Phenotype property assayed	Parkinson's disease
Used in Study	GWAS of Parkinson's disease (HGVST6)
Description	CASES : Disease onset was defined as the time when symptoms of the disease were first noted, including at least one of the following, resting tremor,rigidity.bradykinesia,gait disorder, postuaral instability All Patients were queried about family history of parkinsonism,dementia,tremor,gait disorders and other neurological dysfunction. Both those with and without reported family history were included on the case panel. None were included on the case panel who had three or more relatives with parkinsonism,nor apparent Mendelian inheritance. CONTROLS : None had a history of Alzheimer's disease, amyotrophic lateral sclerosis, ataxia, autism, bipolar disorder, brain aneurysm, dementia, dystonia, or Parkinson's disease. Folstein mini-mental state examination scores ranged from 26â30. All participants were interviewed for family history in detail. None had any first-degree relative with a known primary neurological disorder, including amyotrophic lateral sclerosis, ataxia, autism, brain aneurysm, dystonia, Parkinson's disease, and schizophrenia.
Variable type	Nominal
Variable unit	Not supplied
Cross-references	Not supplied
Phenotype annotation	MeSH: Parkinson Disease (D010300)

Method details